術後化学放射線療法
Long-Term Update of a Phase 3 Randomized Study Comparing Once-a-Week Versus Once-Every-3-Weeks Cisplatin Along With Radiation in Head and Neck Cancer.Noronha V, Patil V, Menon N, et al. Int J Radiat Oncol Biol Phys. 2025 Jan 1;121(1):128-1…
Once-a-Week Versus Once-Every-3-Weeks Cisplatin Chemoradiation for Locally Advanced Head and Neck Cancer: A Phase III Randomized Noninferiority Trial.Noronha V, Joshi A, Patil VM, et al. J Clin Oncol. 2018 Apr 10;36(11):1064-1072. doi: 10.…
Standard versus fractionated high-dose cisplatin plus radiation for locally advanced head and neck cancer: Results of the CisFRad (GORTEC 2015-02) randomized phase II trial.Borel C, Sun XS, Coutte A, et al. Radiother Oncol. 2024 Aug;197:11…
【JCOG 1008：第II相/III相ランダム化試験】局所進行頭頸部扁平上皮がんの高リスク例に対する術後化学放射線療法：シスプラチン 40 mg/m² 毎週投与 vs 100 mg/m² 3週毎投与
Weekly Cisplatin Plus Radiation for Postoperative Head and Neck Cancer (JCOG1008): A Multicenter, Noninferiority, Phase II/III Randomized Controlled Trial. Kiyota N, Tahara M, Mizusawa J, et al. J Clin Oncol. 2022 Jun 20;40(18):1980-1990. …
De-escalated adjuvant radiotherapy versus standard adjuvant treatment for human papillomavirus-associated oropharyngeal squamous cell carcinoma (MC1675): a phase 3, open-label, randomised controlled trial.Ma D, Price K, Moore E, et al. Lan…
Chemoradiotherapy With or Without Simultaneous Integrated Boost for Cervical Cancer With Full-Thickness Stromal Invasion: A Phase 3 Randomized Clinical Trial.Liu S, Fang C, Wu X, et al. JAMA Netw Open. 2025 Sep 2;8(9):e2532501. doi: 10.100…
Adjuvant Chemoradiotherapy Versus Chemotherapy Alone After Resection of Gallbladder Carcinoma: A Real-World, IPTW-Based Cohort Study.Zheng Q, Lyu B, Chen Y, et al. Int J Radiat Oncol Biol Phys. 2025 Sep 16:S0360-3016(25)06284-4. doi: 10.10…
Randomized Phase III Trial of Adjuvant Radiation versus Chemoradiation in Intermediate-Risk, Early-stage Cervical Cancer following Radical Hysterectomy and Lymphadenectomy: Results from NRG Oncology/GOG-263/KGOG1008.Ryu SY, Deng W, Albuque…
Adjuvant chemoradiotherapy versus radiotherapy alone in women with high-risk endometrial cancer (PORTEC-3): 10-year clinical outcomes and post-hoc analysis by molecular classification from a randomised phase 3 trial.Post CCB, de Boer SM, P…
Long-Term Survival Analysis of Neoadjuvant Chemoradiotherapy Versus Adjuvant Chemoradiotherapy for Locally Advanced Low Rectal Cancer.Chen S, Wu R, Wan J, et al. Cancer Med. 2025 Aug;14(15):e71042. DOI: 10.1002/cam4.71042. PMID: 40709606. …
Re-examining Post-operative Chemoradiotherapy in Head and Neck Cancer: An Updated Long-Term Combined Analysis of RTOG 9501/EORTC 22931. Zumsteg ZS, Luu M, Fortpied C, et al. Ann Oncol. 2025 Jul 16:S0923-7534(25)00853-1. DOI: 10.1016/j.anno…
Neoadjuvant and Adjuvant Pembrolizumab in Locally Advanced Head and Neck Cancer. Uppaluri R, Haddad RI, Tao Y, et al. N Engl J Med. 2025 Jul 3;393(1):37-50. DOI: 10.1056/NEJMoa2415434. Epub 2025 Jun 18. PMID: 40532178. 【背景と目的】・局所…
Lack of Survival Benefit with Immunotherapy in Combination with Adjuvant Chemoradiation in Pathologic Stage II-IIIB Non-small Cell Lung Cancer.Venugopal N, Vazquez-Urrutia JR, Zhu J, et al. Ann Surg Oncol. 2025 Jul 17.DOI: 10.1245/s10434-0…
