TNT
Total neoadjuvant therapy with mFOLFIRINOX versus preoperative chemoradiotherapy in patients with locally advanced rectal cancer: long-term results of the UNICANCER-PRODIGE 23 trial. Conroy T, Castan F, Etienne PL, et al. Ann Oncol. 2024 O…
Neoadjuvant short-course radiotherapy followed by camrelizumab and chemotherapy in locally advanced rectal cancer (UNION): early outcomes of a multicenter randomized phase III trial.Lin ZY, Zhang P, Chi P, et al. Ann Oncol. 2024 Oct;35(10)…
Chemoradiotherapy plus induction or consolidation chemotherapy as total neoadjuvant therapy for locally advanced rectal cancer: Pooled analysis of the CAO/ARO/AIO-12 and the OPRA randomized phase 2 trials.Fokas E, Williams H, Diefenhardt M…
Multicenter, Randomized, Phase III Trial of Short-Term Radiotherapy Plus Chemotherapy Versus Long-Term Chemoradiotherapy in Locally Advanced Rectal Cancer (STELLAR).Jin J, Tang Y, Hu C, et al. J Clin Oncol. 2022 May 20;40(15):1681-1692. do…
Post-hoc analysis of clinicopathological factors affecting lateral lymph node metastasis based on STELLAR study for rectal cancer. Chen LN, Jiang J, Jiang LM, et al. Radiother Oncol. 2024 Nov;200:110512. doi: 10.1016/j.radonc.2024.110512. …
Differential effects of RAS mutations on chemoradiotherapy and total neoadjuvant therapy in locally advanced rectal cancer. Haraguchi E, Akiyoshi T, Noguchi T, et al. Int J Cancer. 2025 Jul 14. DOI: 10.1002/ijc.70040 Epub ahead of print. P…
Total neoadjuvant therapy with mFOLFIRINOX versus preoperative chemoradiotherapy in patients with locally advanced rectal cancer: long-term results of the UNICANCER-PRODIGE 23 trial. Conroy T, Castan F, Etienne PL, et al. Ann Oncol. 2024 O…
Neoadjuvant chemotherapy with FOLFIRINOX and preoperative chemoradiotherapy for patients with locally advanced rectal cancer (UNICANCER-PRODIGE 23): a multicentre, randomised, open-label, phase 3 trial.Conroy T, Bosset JF, Etienne PL, et a…
Total neoadjuvant treatment with short-course radiotherapy followed by sintilimab plus capecitabine-oxaliplatin versus short-course radiotherapy followed by capecitabine-oxaliplatin in patients with locally advanced rectal cancer (SPRING-0…
Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer.Audisio A, Gallio C, Velenik V, et al. JAMA Oncol. 2025 Jul 10. DOI: 10.1001/jamaoncol.2025.2026. Epub ahead of print. PMID: 40638097. ・近年、局所進行直腸がん（LARC）の治療戦略…
